What is Inters Ium organ? Interstitium
The scientist has recently discovered this Inters lum organ which is a part of human body. It is believed it could help in curing cancer. Defined updates have yet not arrived. So stay tuned to learn more about Inters lum organ.
Meet Your Interstitium, A Newfound ‘Organ’
With all that’s known about human anatomy, you wouldn’t expect doctors to discover a new body part in this day and age. But now, researchers say they’ve done just that: They’ve found a network of fluid-filled spaces in tissue that hadn’t been seen before.
Previously, researchers had thought these tissue layers were a dense “wall” of collagen — a strong structural protein found in connective tissue. But the new finding reveals that, rather than a “wall,” this tissue is more like an “open, fluid-filled highway,” said co-senior study author Dr. Neil Theise, a professor of pathology at New York University Langone School of Medicine.
The researchers said these fluid-filled spaces had been missed for decades because they don’t show up on the standard microscopic slides that researchers use to peer into the cellular world. When scientists prepare tissue samples for these slides, they treat the samples with chemicals, cut them into thin slices and dye them to highlight key features. But this fixing process drains away fluid and causes the newfound fluid-filled spaces to collapse.
A new organ?
The human body is about 60 percent water. About two-thirds of that water is found inside cells, but the other third is outside cells and is known as “interstitial” fluid. Although researchers already knew that there is fluid between individual cells, the idea of a larger, connected interstitium — in which there are fluid-filled spaces within tissues — had been described only vaguely in the literature, Theise said. The new study, he said, expands the concept of the interstitium by showing these structured, fluid-filled spaces within tissues, and is the first to define the interstitium as an organ in and of itself.
The new work is based on the use of a relatively new technology called a “probe-based confocal laser endomicroscopy” or pCLE. This tool combines an endoscope with a laser and sensors that analyze reflected fluorescent patterns and gives researchers a microscopic view of living tissues.
Back in 2015, two of the study authors — Dr. David Carr-Locke and Dr. Petros Benias, both of whom were at Mount Sinai-Beth Israel Medical Center in New York City at the time — were using this technology when they saw something unusual while examining a patient’s bile duct for cancer spread. They spotted a series of interconnected cavities in the tissue layer that didn’t match any known anatomy, according to the report. When a pathologist made slides out of this tissue, the cavities disappeared — a mystery that was later found to be a consequence of the slide-making process.
Later, the researchers saw these same fluid-filled spaces in other samples of connective tissue taken from other parts of the body, in people without cancer, Theise said. “The more tissues I saw, the more I realized it’s everywhere,” he said.
The researchers think that the fluid-filled spaces may act as shock absorbers to protect tissues during daily functions, the researchers said.
They noted that there may be quite a bit of information already known about this fluid-filled space; it’s just that researchers “didn’t know what they were looking at.” Indeed, the researchers plan to conduct a review of the scientific literature “for all the things we know about this [body part] but didn’t know we knew it,” Theise said.